1. Grotewold E. The genetics and biochemistry of floral pigments[J]. Annual Review of Plant Biology,2006,57:761-780. 2. Tanaka Y,Sasaki N,Ohmiya A. Biosynthesis of plant pigments:anthocyanins,betalains and carotenoids[J]. The Plant Journal,2008,549(4):733-749. 3. Tanaka Y,Brugliera F. Flower colour and cytochromes P450[J]. Philosophical Transactions of the Royal Society B:Biological Sciences,2013,368(1612):20120432,doi:10. 1098/rstb. 2012. 0432. 4. 朱长甫,陈星,王英典. 植物类胡萝卜素生物合成及其相关基因在基因工程中的应用[J]. 植物生理与分子生物学学报,2004,30(6):609-618.Zhu C F,Chen X,Wang Y D. Carotenoid biosynthesis in plants and application of its relative genes in gene engineering[J]. Journal of Plant Physiology and Molecular Biology,2004,30(6):609-618. 5. Zhu C F,Bai C,Sanahuja G,et al. The regulation of carotenoid pigmentation in flowers[J]. Archives of Biochemistry and Biophysics,2010,504(1):132-141. 6. Zhang Y,Butelli E,Martin C. Engineering anthocyanin biosynthesis in plants[J]. Current Opinion in Plant Biology,2014,19:81-90. 7. 倪勤学,霍艳荣,陆国权. 花色苷保健功能的研究进展[J]. 安徽农业科学,2010,38(35):20025-20028,20453.Ni Q X,Huo Y R,Lu G Q. Advances in health functions of anthocyanins[J]. Journal of Anhui Agricultural Science,2010,38(35):20025-20028,20453. 8. 刘仕芸,黄艳岚,张树珍. 植物花青素生物合成中的调控基因[J]. 植物生理学通讯,2006,42(4):747-754.Liu S Y,Huang Y L,Zhang S Z. Regulatory gene of anthocyanin biosynthesis in plant[J]. Plant Physiology Communications,2006,42(4):747-754. 9. 黄鸿曼,袁利兵,彭志红,等. 花青素的生物合成与环境调控研究进展[J]. 湖南农业科学,2011,(13):118-120.Huang H M,Yuan L B,Peng Z H,et al. Advances in biosynthesis and environmental regulation of anthocyanin[J]. Hunan Agricultural Sciences,2011,(13):118-120. 10. Berman J,Sheng Y M,Gómez L G,et al. Red anthocyanins and yellow carotenoids form the color of orange-flower gentian(Gentiana lutea L. var. aurantiaca)[J]. PLoS One,2016,11(9):e0162410,doi:10. 1371/journal. pone. 0162410. 11. Tian J,Han Z Y,Zhang J,et al. The balance of expression of dihydroflavonol 4-reductase and flavonol synthase regulates flavonoid biosynthesis and red foliage coloration in crabapples[J]. Scientific Reports,2015,5:12228,doi:10. 1038/srep12228. 12. 石少川,高亦珂,张秀海,等. 植物花青素生物合成相关基因的研究及应用[J]. 植物研究,2011,31(5):633-640.Shi S C,Gao Y K,Zhang X H,et al. Progress on plant genes involved in biosynthetic pathway of anthocyanins[J]. Bulletin of Botanical Research,2011,31(5):633-640. 13. 罗庆林,邵继荣,胡建平,等. 荞麦中类黄酮的研究进展[J]. 食品研究与开发,2008,29(2):160-164.Luo Q L,Shao J R,Hu J P,et al. Research progress of flavaniods in Buckwheat[J]. Food Research and Development,2008,29(2):160-164. 14. Petit P,Granier T,D'estaintot B L,et al. Crystal structure of grape dihydroflavonol 4-reductase,a key enzyme in flavonoid biosynthesis[J]. Journal of Molecular Biology,2007,368(5):1345-1357. 15. Matsui K,Hisano T,Yasui Y,et al. Isolation and characterization of genes encoding leucoanthocyanidin reductase(FeLAR) and anthocyanidin reductase(FeANR) in buckwheat(Fagopyrum esculentum)[J]. Journal of Plant Physiology,2016,205:41-47. 16. 张龙,李卫华,姜淑梅,等. 花色素苷生物合成与分子调控研究进展[J]. 园艺学报,2008,35(6):909-916.Zhang L,Li W H,Jiang S M,et al. Progress of molecular basis of biosynthesis and transcriptional regulation of anthocyanins[J]. Acta Horticulturae Sinica,2008,35(6):909-916. 17. Davies K M,Schwinn K E,Deroles S C,et al. Enhancing anthocyanin production by altering competition for substrate between flavonol synthase and dihydroflavonol 4-reductase[J]. Euphytica,2003,131(3):259-268. 18. 高燕会,黄春红,朱玉球,等. 植物花青素苷生物合成及调控的研究进展[J]. 中国生物工程杂志,2016,32(8):94-99.Gao Y H,Huang C H,Zhu Y Q,et al. Progress on plant anthocyanin biosynthesis and regulation[J]. China Biotechnology,2016,32(8):94-99. 19. 祝志欣,鲁迎青. 花青素代谢途径与植物颜色变异[J]. 植物学报,2016,51(1):107-119.Zhu Z X,Lu Y C. Plant color mutants and the anthocyanin pathway[J]. Chinese Bulletin of Botany,2016,51(1):107-119. 20. 梁平,宋洪元. 植物花青素生物合成转录调控研究进展[J]. 南方农业学报,2014,45(8):1375-1379.Liang P,Song H Y. Advances on the transcriptional regulation of anthocyanin biosynthesis in plant[J]. Journal of Southern Agriculture,2014,45(8):1375-1379. 21. 梅菊芬,徐德良,汤茶琴,等. 茶树花青素及其种质资源的研究和利用进展[J]. 热带农业工程,2013,37(1):42-46.Mei J F,Xu D L,Tang C Q,et al. Advances on research and utilization of tea tree(Camellia sinensis) anthocyanins and its germplasm resources[J]. Tropical Agricultural Engineering,2013,37(1):42-46. 22. Ramsay N A,Glover B J. MYB-bHLH-WD40 protein complex and the evolution of cellular diversity[J]. Trends in Plant Science,2005,10(2):63-70. 23. Hichri I,Barrieu F,Bogs J,et al. Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway[J]. Journal of Experimental Botany,2011,62(8):2465-2483. 24. Xu W J,Dubos C,Lepiniec L. Transcriptional control of flavonoid biosynthesis by MYB-bHLH-WDR complexes[J]. Trends in Plant Science,2015,20(3):176-185. 25. Zhu Z X,Wang H L,Wang Y T,et al. Characterization of the cis elements in the proximal promoter regions of the anthocyanin pathway genes reveals a common regulatory logic that governs pathway regulation[J]. Journal of Experimental Botany,2015,66(13):3775-3789. 26. Hernandez J M,Heine G F,Irani N G,et al. Different mechanisms participate in the R-dependent activity of the R2R3 MYB transcription factor C1[J]. Journal of Biological Chemistry,2004,279(46):48205-48213. 27. Hartmann U,Sagasser M,Mehrtens F,et al. Differential combinatorial interactions of cis-acting elements recognized by R2R3-MYB,BZIP,and BHLH factors control light-responsive and tissue-specific activation of phenylpropanoid biosynthesis genes[J]. Plant Molecular Biology,2005,57(2):155-171. 28. Dare A P,Schaffer R J,Kui L W,et al. Identification of a cis-regulatory element by transient analysis of co-ordinately regulated genes[J]. Plant Methods,2008,4:17,doi:10. 1186/1746-4811-4-17. 29. Wang H L,Guan S,Zhu Z X,et al. A valid strategy for precise identifications of transcription factor binding sites in combinatorial regulation using bioinformatic and experimental approaches[J]. Plant Methods,2013,9(1):34,doi:10. 1186/1746-4811-9-34. 30. Meyer P,Heidmann I,Forkmann G,et al. A new Petunia flower colour generated by transformation of a mutant with a maize gene[J]. Nature,1987,330(6149):677-678. 31. Johnson E T,Yi H,Shin B,et al. Cymbidium hybrida dihydroflavonol 4-reductase does not efficiently reduce dihydrokaempferol to produce orange pelargonidin-type anthocyanins[J]. The Plant Journal,1999,19(1):81-85. 32. Johnson E T,Ryu S,Yi H,et al. Alteration of a single amino acid changes the substrate specificity of dihydroflavonol 4-reductase[J]. The Plant Journal,2001,25(3):325-333. 33. 樊云芳,陈晓军,李彦龙,等. 宁夏枸杞DFR基因的克隆与序列分析[J]. 西北植物学报,2011,31(12):2373-2379.Fan Y F,Chen X J,Li Y L,et al. Cloning and sequence analysis of dihydroflavonol 4-reductase gene from Lycium barbarum[J]. Acta Botanica Boreali-Occidentalia Sinica,2011,31(12):2373-2379. 34. Forkmann G,Ruhnau B. Distinct substrate specificity of dihydroflavonol 4-reductase from flowers of Petunia hybrida[J]. Zeitschrift für Naturforschung C,1987,42(9-10):1146-1148. 35. Beld M,Martin C,Huits H,et al. Flavonoid synthesis in Petunia hybrida:partial characterization of dihydroflavonol-4-reductase genes[J]. Plant Molecular Biology,1989,13(5):491-502. 36. Xie D Y,Jackson L A,Cooper J D,et al. Molecular and biochemical analysis of two cDNA clones encoding dihydroflavonol-4-reductase from Medicago truncatula[J]. Plant Physiology,2004,134(3):979-994. 37. Miosic S,Thill J,Milosevic M,et al. Dihydroflavonol 4-reductase genes encode enzymes with contrasting substrate specificity and show divergent gene expression profiles in Fragaria species[J]. PLoS One,2014,9(11):e112707,doi:10. 1371/journal. pone. 0112707. 38. Sasaki N,Nakayama T. Achievements and perspectives in biochemistry concerning anthocyanin modification for blue flower coloration[J]. Plant and Cell Physiology,2015,56(1):28-40. 39. Nakatsuka T,Abe Y,Kakizaki Y,et al. Production of red-flowered plants by genetic engineering of multiple flavonoid biosynthetic genes[J]. Plant Cell Reports,2007,26(11):1951-1959. 40. Yuan Y W,Rebocho A B,Sagawa J M,et al. Competition between anthocyanin and flavonol biosynthesis produces spatial pattern variation of floral pigments between Mimulus species[J]. Proceedings of National Academy of Sciences of the United States of America,2016,113(9):2448-2453. 41. Luo P,Ning G G,Wang Z,et al. Disequilibrium of flavonol synthase and dihydroflavonol-4-reductase expression associated tightly to white vs. red color flower formation in plants[J]. Frontiers in Plant Science,2016,6:1257,doi:10. 3389/fpls. 2015. 01257. 42. Helariutta Y,Elomaa P,Kotilainen M,et al. Cloning of cDNA coding for dihydroflavonol-4-reductase(DFR) and characterization of dfr expression in the corollas of Gerbera hybrida var. regina(Compositae)[J]. Plant Molecular Biology,1993,22(2):183-193. 43. Tanaka Y,Brugliera F,Chandler S. Recent progress of flower colour modification by biotechnology[J]. International Journal of Molecular Sciences,2009,10(12):5350-5369. 44. Tanaka Y,Tsuda S,Kusumi T. Metabolic engineering to modify flower color[J]. Plant Cell and Physiology,1998,39(11):1119-1126. 45. 周惠,文锦芬,邓明华,等. 植物花青素生物合成相关基因研究进展[J]. 辣椒杂志,2011,(4):1-7.Zhou H,Wen J F,Deng M H,et al. Research progress in plant anthocyanidin biosynthesis genes[J]. Journal of China Capsicum,2011,(4):1-7. 46. Itoh Y,Higeta D,Suzuki A,et al. Excision of transposable elements from the chalcone isomerase and dihydroflavonol 4-reductase genes may contribute to the variegation of the yellow-flowered carnation(Dianthus caryophyllus)[J]. Plant and Cell Physiology,2002,43(5):578-585. 47. Aida R,Yoshida K,Kondo T,et al. Copigmentation gives bluer flowers on transgenic torenia plants with the antisense dihydroflavonol-4-reductase gene[J]. Plant Science,2000,160(1):49-56. 48. Seitz C,Vitten M,Steinbach P,et al. Redirection of anthocyanin synthesis in Osteospermum hybrida by a two-enzyme manipulation strategy[J]. Phytochemistry,2007,68(6):824-833. 49. Nakamura N,Fukuchi-Mizutani M,Fukui Y,et al. Generation of pink flower varieties from blue Torenia hybrida by redirecting the flavonoid biosynthetic pathway from delphinidin to pelargonidin[J]. Plant Biotechnology,2010,27(5):375-383. 50. Lee W S,You J A,Chung H,et al. Molecular cloning and biochemical analysis of dihydroflavonol 4-reductase(DFR) from Brassica rapa ssp. pekinesis(Chinese Cabbage) using a heterologous system[J]. Journal of Plant Biology,2008,51(1),42-47. 51. Huang Y,Gou J Q,Jia Z C,et al. Molecular cloning and characterization of two genes encoding dihydroflavonol-4-reductase from Populus trichocarpa[J]. PLoS One,2012,7(2):e30364,doi:10. 1371/journal. pone. 0030364. 52. 李义龙,肇涛澜,陈立超,等. 花色素苷生物合成及花色的调控[J]. 生命科学,2008,20(1):147-152.Li Y L,Zhao T L,Chen L C,et al. Regulation in pigment biosynthesis and color variation of flowers[J]. Chinese Bulletin of Life Sciences,2008,20(1):147-152. 53. Hayashi M,Takahashi H,Tamura K,et al. Enhanced dihydroflavonol-4-reductase activity and NAD homeostasis leading to cell death tolerance in transgenic rice[J]. Proceedings of National Academy of Sciences of the United States of America,2005,102(19):7020-7025. 54. Kumar V,Nadda G,Kumar S,et al. Transgenic tobacco overexpressing tea cDNA encoding dihydroflavonol 4-reductase and anthocyanidin reductase induces early flowering and provides biotic stress tolerance[J]. PLoS One,2013,8(6):e65535,doi:10. 1371/journal. pone. 0065535. 55. Li Y Q,Liu X X,Cai X Q,et al. Dihydroflavonol 4-reductase genes from Freesia hybrida play important and partially overlapping roles in the biosynthesis of flavonoids[J]. Frontiers in Plant Science,2017,8:428,doi:10. 3389/fpls. 2017. 00428. |