油樟(Cinnamomum longepaniculatum)精油的抗炎及抗氧化活性初步研究

doi:10.7525/j.issn.1673-5102.2016.06.020

植物研究 ›› 2016, Vol. 36 ›› Issue (6): 949-954.doi: 10.7525/j.issn.1673-5102.2016.06.020

油樟(Cinnamomum longepaniculatum)精油的抗炎及抗氧化活性初步研究

丛赢, 张琳, 祖元刚, 杨磊, 昝鹏

东北林业大学森林植物生态学教育部重点实验室, 哈尔滨 150040

收稿日期:2016-06-04 出版日期:2016-11-15 发布日期:2016-11-16
通讯作者: 张琳,E-mail:zhanglin6600@sina.com E-mail:zhanglin6600@sina.com
作者简介:丛赢(1990-),女,硕士研究生,主要从事植物资源开发与利用。
基金资助:
公益性行业科研专项经费项目（20140460202）

Anti-inflammatory and Antioxidant Activity of Cinnamomum longepaniculatum Essential Oil

CONG Ying, ZHANG Lin, ZU Yuan-Gang, YANG Lei, ZAN Peng

Key Laboratory of Forest Plant Ecology, Northeast Forestry University, Harbin 150040

Received:2016-06-04 Online:2016-11-15 Published:2016-11-16
Supported by:
Special Fund for Forestry Scientific Research in the Public Interest(20140460202)

摘要/Abstract

摘要： 通过MTT检验和NO含量测定，观察油樟精油对LPS致炎RAW264.7巨噬细胞的抗炎作用；通过角叉菜胶足肿胀致炎模型检测油樟精油的体内抗炎活性；并采用DPPH·自由基清除能力检测油樟精油的抗氧化能力。结果表明：油樟精油能够降低LPS诱导的RAW264.7巨噬细胞致炎模型的细胞抑制率并减少模型细胞一氧化氮（NO）产量；对角叉菜胶所致大鼠足肿胀有减缓效果且呈剂量依赖性；能够使DPPH·自由基清除率显著增加，并随时间延长效果更显著。表明油樟精油具有一定的抗炎及抗氧化活性。

关键词: 油樟, 精油, 抗氧化, 抗炎

Abstract: Anti-inflammatory effect of Cinnamomum longepaniculatum essential oil on LPS-induced RAW264.7 macrophages inflammation was observed by MTT test and the content of NO. In vivo, anti-inflammatory activity was carried by checking carrageenan-induced rat paw swelling degree treated with C.longepaniculatum essential oil. The antioxidant capacity was determined by measuring DPPH·radical scavenging ability. C.longepaniculatum essential oil can reduce the inhibition rate and NO production of the LPS-induced RAW264.7 macrophage and it can also reduce carrageenan-induced rat paw swelling with dose-dependent manner. C.longepaniculatum essential oil can induce DPPH radical scavenging rate increased significantly, and the effect is more significant with time. Therefore, C.longepaniculatum oil has anti-inflammatory and anti-oxidant activity.

Key words: Cinnamomum longepaniculatum, essential oil, anti-inflammatory activity, antioxidant activity

中图分类号:

S792.23

丛赢, 张琳, 祖元刚, 杨磊, 昝鹏. 油樟(Cinnamomum longepaniculatum)精油的抗炎及抗氧化活性初步研究[J]. 植物研究, 2016, 36(6): 949-954.

CONG Ying, ZHANG Lin, ZU Yuan-Gang, YANG Lei, ZAN Peng. Anti-inflammatory and Antioxidant Activity of Cinnamomum longepaniculatum Essential Oil[J]. Bulletin of Botanical Research, 2016, 36(6): 949-954.

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油樟(Cinnamomum longepaniculatum)精油的抗炎及抗氧化活性初步研究

Anti-inflammatory and Antioxidant Activity of Cinnamomum longepaniculatum Essential Oil

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