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植物研究 ›› 2024, Vol. 44 ›› Issue (6): 805-811.doi: 10.7525/j.issn.1673-5102.2024.06.001

• 研究综述 •    下一篇

液-液相分离机制介导的基因表达调节植物生长发育和抗逆性状研究进展

徐晴晴, 孙德辉, 王文梦, 李当当, 蓝兴国, 隋广超()   

  1. 东北林业大学生命科学学院,哈尔滨 150040
  • 收稿日期:2024-05-14 出版日期:2024-11-20 发布日期:2024-11-22
  • 通讯作者: 隋广超 E-mail:gcsui@nefu.edu
  • 作者简介:徐晴晴(1998—),女,博士研究生,主要从事表观遗传学研究。
  • 基金资助:
    国家自然科学基金项目(82273107);中央高校基本科研业务费专项资金项目(2572022DQ06)

Research Progress of Plant Growth, Development and Stress Resistance Traits Regulated by Liquid-liquid Phase Separation-mediated Gene Expression

Qingqing XU, Dehui SUN, Wenmeng WANG, Dangdang LI, Xingguo LAN, Guangchao SUI()   

  1. College of Life Sciences,Northeast Forestry University,Harbin 150040
  • Received:2024-05-14 Online:2024-11-20 Published:2024-11-22
  • Contact: Guangchao SUI E-mail:gcsui@nefu.edu

摘要:

基因表达决定了多细胞生物的生长、分化及各种性状和功能,而转录调控是基因表达过程中最为关键的步骤之一。自2018年以来,生物大分子形成的液-液相分离凝聚体对哺乳动物细胞中基因表达的调控机制被不断深入揭示,然而,对相分离在植物细胞内调控基因转录过程的机制研究还相对较少。该文首先介绍了真核细胞内生物大分子形成的液-液相分离调控基因表达的基本形式和研究方法,然后重点阐述了目前已有的相分离机制通过介导基因转录以调节植物生长发育和抗逆性状的报道,最后对植物中拓宽和加深相分离调控基因表达研究进行展望。

关键词: 液-液相分离, 生物大分子, 植物细胞, 基因表达, 转录调控

Abstract:

Gene expression determines the growth, differentiation, and various traits and functions of multicellular organisms. In this process, transcriptional regulation is one of the most critical steps of gene expression. Since 2018, gene expressions regulated by the liquid-liquid phase-separated condensates formed by biological macromolecules in mammalian cells have been continuously revealed. However, the research in understanding the role of phase separation in the gene transcription process of plant cells has achieved relatively limited progression. In this review, we first introduced the mechanisms of phase separation-regulated gene expression, discussed its relevant basic research approaches, and summarized key findings in the mechanistic studies of phase separation in regulating gene transcription during the growth, development and stress response of plants. Finally, we provided our perspectives for future researches to expand and deepen the understanding of phase separation regulation mechanisms of plant gene expression.

Key words: liquid-liquid phase separation, biological macromolecules, plant cells, gene expression, transcriptional regulation

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