玄参的化学成分研究

doi:10.7525/j.issn.1673-5102.2008.02.026

植物研究 ›› 2008, Vol. 28 ›› Issue (2): 254-256.doi: 10.7525/j.issn.1673-5102.2008.02.026

• 论文 • 上一篇

玄参的化学成分研究

姜守刚¹;蒋建勤²;祖元刚^1*

(1.东北林业大学森林植物生态学教育部重点实验室，哈尔滨　150040) (2.中国药科大学中药学院，南京　210038)

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-03-20 发布日期:2008-03-20
通讯作者: 祖元刚
基金资助:

Chemical Components from the Root of Scrophularia ningpoensis

JIANG Shou-Gang;JIANG Jian-Qin;ZU Yuan-Gang*

(1.Key Laboratory of Forest Plant Ecology,Ministry of Education,Northeast Forestry University,Harbin　150040) (2.School of Chinese Materia Medica,China Pharmaceutical University,Nanjing　210038)

Received:1900-01-01 Revised:1900-01-01 Online:2008-03-20 Published:2008-03-20
Contact: ZU Yuan-Gang
Supported by:

摘要/Abstract

摘要： 利用正、反相硅胶以及各种色谱技术进行分离，经理化性质和光谱分析鉴定中药玄参(Scrophularia ningpoensis)有效成分。从玄参(S. ningpoensis)根的乙醇提取物中分离了8个化合物，分别鉴定为14-去氧-12(R)-磺酸基穿心莲内酯（14-deoxy-12(R)-sulfo andrographolide， Ⅷ）、肉桂酸（cinnamic acid，Ⅰ）、对羟基肉桂酸（p-hydroxycinnamic acid，Ⅱ）、丁二酸（succinic acid，Ⅲ）、β-谷甾醇（β-sitosterol， Ⅳ）、胡萝卜甙（daucosteol，Ⅴ）、葡萄糖（gluose，Ⅵ）、熊果酸(ursolic acid，Ⅶ)。Ⅷ为在玄参中首次发现的天然化合物。

关键词: 玄参, 二萜, 14-去氧-12(R)-磺酸基穿心莲内酯

Abstract: To search new anti-infective from Scrophularia ningpoensis. Various column chromatographic techniques were used for isolation and purification of the principles. The structures were elucidated on the basis of spectral data(UV,IR,MS,NMR) and identified by comparing with the authentic substance eight comounds were isolated from ethyl alcohol extract, They are identified as: 14-deoxy-12(R)-sulfo andrographolide(Ⅷ),cinnamic acid(Ⅰ),p-hydroxycinnamic acid(Ⅱ),succinic acid(Ⅲ),β-sitosterol(Ⅳ),daucosteol(Ⅴ),gluose(Ⅵ),ursolic acid(Ⅶ).Ⅷ was found first time in Scrophularia ningpoensis.

Key words: Scrophularia ningpoensis Hemsl, diterpenoid, 14-deoxy-12(R)-sulfo andrographolide

中图分类号:

姜守刚;蒋建勤;祖元刚*. 玄参的化学成分研究[J]. 植物研究, 2008, 28(2): 254-256.

JIANG Shou-Gang;JIANG Jian-Qin;ZU Yuan-Gang*. Chemical Components from the Root of Scrophularia ningpoensis[J]. Bulletin of Botanical Research, 2008, 28(2): 254-256.

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玄参的化学成分研究

Chemical Components from the Root of Scrophularia ningpoensis

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