关键词: 疟疾, 青蒿素, 黄花蒿, 无载体固定化

Abstract: Malaria is a kind of serious pandemic which is caused by plasmodia through mosquito's sting and bite. At present, drugs of curing malaria are:chloroquine, ethylamine pyrimidine et al, but the most serious question is anti-drug character of plasmodia on those drugs, particular to chloroquine. Furthermore, the anti-chloroquine plasmodia strain have cross-anti character in clinical. Artemisinin from Artemisia annua L. has evidently anti-malaria activity and become the best drug in clinical. At present, the key question is that how to acquire artemisinin. For this reason we utilize self-immobilized aggregate culture of Artemisia annua L. to produce Artemisinin, and primarily studied character of self-immobilized culture of Artemisia annua L. cell. Through determining, it find that this method can acquire 9-times quantity artemisinin more than normal method. Therefore this method may be possible became the best method of artemisinin produce.

Key words: malaria, artemisinin, Artemisia annua L., self-immobilized aggregate