Abstract: The response of T. chinensis TC158 cell line to the addition of precursors/regulators of taxol is described in this paper. On the 25th day after inoculation, cell cultures were supplemented with different concentrations of one of the following compounds:sodium acetate, sodium benzoate, L-phenylalanine, glycine, L-serine, α-pinene and turpentine oil. The results demonstrated that taxol biosynthesis was improved in different degrees, while the cell growth was not significantly affected by various precursors/regulators.

Key words: Precursor, Taxol, Cell culture, Taxus chinensis