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Bulletin of Botanical Research ›› 2016, Vol. 36 ›› Issue (4): 634-640.doi: 10.7525/j.issn.1673-5102.2016.04.021

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Extraction and Anti-inflammatory of Korean Pine Polyphenol

ZU Yuan-Gang1,2, HU Yan1,2, JIANG Shou-Gang1,2   

  1. 1. Key Laboratory of Forest Plant Ecology, Northeast Forestry University, Harbin 150040;
    2. State Engineering Laboratory of Bio-Resources Eco-Utilization, Northeast Forestry University, Harbin 150040
  • Received:2016-02-27 Online:2016-07-15 Published:2016-06-15
  • Supported by:
    The Twelfth Five-Year National Science and technology supportprogram in rural areas;The key technology research and demonstration of the definite cultivation of eucommia ulmoides and camptotheca acuminate precious ingredients and medicinal forest(2012BAD21B0501-11);The Fundamental Research Funds for the Central Universities;Preparation and preclinical medicine evaluation of paclitaxelnanoparticles(DL13CA11)

Abstract: The ultrasonic extraction process was used to extract polyphenols in Korean pine bark, with the polyphenol yield as index. The optimum conditions were obtained through single factor test and orthogonal test with 4 factors of material ratio, ethanol concentration, extract time and extract temperature. The optimal ultrasonic extract conditions were material ratio(g·mL-1) of 1:30, ethanol concentration of 60%, extract time of 2.0 h, and extract temperature of 80℃. For the anti-inflammatory effect of Korean pine polyphenol, polar polyphenol and blueberry polyphenol, in 0.01-100 μg·mL-1, the anti-inflammatory effect order was:blueberry polyphenol> Korean pine polyphenol> polar polyphenol.

Key words: korean pine polyphenol, ultrasonic extract, anti-inflammatory, polar polyphenol, blueberry polyphenol

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